Multifunctional one-droplet microfluidic chemosensing of ractopamine in real samples: a user-oriented flexible nano-architecture for on-site food and pharmaceutical analysis using optical sensors

Illegal use of ractopamine (RAC) in the food industry has dire consequences for health which should be curbed by inexpensive on-site checks. In this study, four advanced nanostructures of AuNPs were examined for this purpose. For the first time, a novel cost-effective colorimetric opto-sensor based...

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Veröffentlicht in:Analytical methods 2023-09, Vol.15 (35), p.456-4517
Hauptverfasser: Baghban, Hossein Navay, Hasanzadeh, Mohammad
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Sprache:eng
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Zusammenfassung:Illegal use of ractopamine (RAC) in the food industry has dire consequences for health which should be curbed by inexpensive on-site checks. In this study, four advanced nanostructures of AuNPs were examined for this purpose. For the first time, a novel cost-effective colorimetric opto-sensor based on gold nanoparticles in aqueous solution was developed and successfully utilized for the recognition of RAC in real samples. The colorimetric chemosensor based on AuNPs-CysA exhibited a linear range of 0.1 μM to 0.01 M with a limit of detection (LOD) of 0.001 μM. Also, using AuNPs-DDT as a photonic probe two ranges of linearity of 0.01 to 50 μM and 0.005 to 0.01 M were obtained (LOD = 1 nM). The outstanding features of the utilized nanostructures are the simple preparation, the suitable stability of AuNPs-CysA and the excellent selectivity of AuNPs-DDT toward RAC recognition. Finally, the engineered colorimetric systems were combined with a simple and inexpensive optimized microfluidic glass fiber-based device. This work paves the way for devising inexpensive and efficient on-site recognition devices for food safety checks. Illegal use of ractopamine (RAC) in the food industry has dire consequences for health which should be curbed by inexpensive on-site checks.
ISSN:1759-9660
1759-9679
1759-9679
DOI:10.1039/d3ay01064c