BF 3 ·OEt 2 -catalyzed synthesis of 2,2′-spirobi-2 H -1-benzopyrans from 2 H -chromenes

BF 3 ·OEt 2 -catalyzed synthesis of 2,2′-spirobi-2 H -1-benzopyrans from 2 H -chromenes

A new BF 3 ·OEt 2 -catalyzed approach was developed for the construction of 2,2′-spirobi-2 H -1-benzopyrancarboxylates by reacting ethyl 2-(chloromethyl)-2-hydroxy-2 H -chromene-3-carboxylates with salicylaldehydes. The reactions proceeded through the formation of C–C and C–O bonds in one pot. Struc...

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Veröffentlicht in:Organic & biomolecular chemistry 2022-10, Vol.20 (41), p.8145-8148
Hauptverfasser: Mudulkar, Sairam, Kolla, Sai Teja, Sridhar, Balasubramanian, Bhimapaka, China Raju
Format: Artikel
Sprache:eng
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Zusammenfassung:A new BF 3 ·OEt 2 -catalyzed approach was developed for the construction of 2,2′-spirobi-2 H -1-benzopyrancarboxylates by reacting ethyl 2-(chloromethyl)-2-hydroxy-2 H -chromene-3-carboxylates with salicylaldehydes. The reactions proceeded through the formation of C–C and C–O bonds in one pot. Structure assignment of compound 3c was confirmed by single crystal X-ray analysis.
ISSN:1477-0520
1477-0539
DOI:10.1039/D2OB01286C