Supersensitive CeO x -based nanocomposite sensor for the electrochemical detection of hydroxyl free radicals

Supersensitive CeO x -based nanocomposite sensor for the electrochemical detection of hydroxyl free radicals

It is well known that an excess of hydroxyl radicals (˙OH) in the human body is responsible for oxidative stress-related diseases. An understanding of the relationship between the concentration of ˙OH and those diseases could contribute to better diagnosis and prevention. Here we present a supersens...

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Veröffentlicht in:Nanoscale 2021-03, Vol.13 (9), p.5136-5144
Hauptverfasser: Duanghathaipornsuk, Surachet, Kim, Dong-Shik, Phares, Tamara L, Li, Cheng-Han, Jinschek, Joerg R, Alba-Rubio, Ana C
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Electrochemical Techniques
Electrodes
Hydrogen Peroxide
Limit of Detection
Mice
Nanocomposites
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Zusammenfassung:It is well known that an excess of hydroxyl radicals (˙OH) in the human body is responsible for oxidative stress-related diseases. An understanding of the relationship between the concentration of ˙OH and those diseases could contribute to better diagnosis and prevention. Here we present a supersensitive nanosensor integrated with an electrochemical method to measure the concentration of ˙OH in vitro. The electrochemical sensor consists of a composite comprised of ultrasmall cerium oxide nanoclusters (
ISSN:2040-3364
2040-3372
DOI:10.1039/d1nr00015b