Catalytic and enantioselective oxa-Piancatelli reaction using a chiral vanadium complex
An enantioselective oxa-Piancatelli reaction was established for the first time using a chiral vanadium( v ) catalyst. The dual Brønsted and Lewis acid properties of the vanadium catalyst afforded 4-hydroxycyclopent-2-enone derivatives in up to 90% yields and with 93 : 7 enantiomeric ratios, as well...
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| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2020-09, Vol.56 (7), p.1151-1154 |
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| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | An enantioselective oxa-Piancatelli reaction was established for the first time using a chiral vanadium(
v
) catalyst. The dual Brønsted and Lewis acid properties of the vanadium catalyst afforded 4-hydroxycyclopent-2-enone derivatives in up to 90% yields and with 93 : 7 enantiomeric ratios, as well as >20 : 1 diastereomeric ratios.
An enantioselective oxa-Piancatelli reaction was established for the first time using a chiral vanadium(
v
) catalyst. |
|---|---|
| ISSN: | 1359-7345 1364-548X |
| DOI: | 10.1039/d0cc02621b |