Quinoline H 2 S donor decorated fluorescent carbon dots: visible light responsive H 2 S nanocarriers

Recent studies have shown that the utility of nanocarriers for the transportation of gaseous signalling molecules to their target site in a biological environment is an effective approach. In this work, we have developed for the first time visible light responsive nanocarriers for the effective rele...

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Veröffentlicht in:Journal of materials chemistry. B, Materials for biology and medicine Materials for biology and medicine, 2020-02, Vol.8 (5), p.1026-1032
Hauptverfasser: Bera, Manoranjan, Maji, Somnath, Paul, Amrita, Sahoo, Bikash Kumar, Maiti, Tapas Kumar, Singh, N D Pradeep
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Sprache:eng
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Zusammenfassung:Recent studies have shown that the utility of nanocarriers for the transportation of gaseous signalling molecules to their target site in a biological environment is an effective approach. In this work, we have developed for the first time visible light responsive nanocarriers for the effective release of H S. Our newly developed nanocarriers for H S release are constructed using two main ingredients: fluorescent carbon dots and quinoline as an H S donor. The developed nanocarriers provided interesting properties like good solubility under physiological conditions, excellent fluorescence properties and efficient release ability of H S with good quantum yield upon visible light irradiation. In vitro studies revealed that our designed nanocarriers exhibited abilities like efficient cellular internalization and good biocompatibility.
ISSN:2050-750X
2050-7518
DOI:10.1039/c9tb02157d