Rose bengal as photocatalyst: visible light-mediated Friedel-Crafts alkylation of indoles with nitroalkenes in water

Rose bengal as photocatalyst: visible light-mediated Friedel-Crafts alkylation of indoles with nitroalkenes in water

A novel and facile visible-light-mediated alkylation of indoles and nitroalkenes has been developed. In this protocol, rose bengal acts as a photosensitizer, and environmentally benign water was used as the green and efficient reaction medium. Indoles reacted smoothly with nitroalkenes under the irr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:RSC advances 2020-01, Vol.10 (8), p.4825-4831
Hauptverfasser: Yu, Zong-Yi, Zhao, Jing-Nan, Yang, Fan, Tang, Xiao-Fei, Wu, Yu-Feng, Ma, Cun-Fei, Song, Bo, Yun, Lei, Meng, Qing-Wei
Format: Artikel
Sprache:eng
Schlagworte:
Alkylation
Chemistry
Indoles
irradiation
light
nitroalkenes
photocatalysts
photosensitizing agents
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A novel and facile visible-light-mediated alkylation of indoles and nitroalkenes has been developed. In this protocol, rose bengal acts as a photosensitizer, and environmentally benign water was used as the green and efficient reaction medium. Indoles reacted smoothly with nitroalkenes under the irradiation of visible-light and generated corresponding 3-(2-nitroalkyl)indoles in moderate to good yields (up to 87%).
ISSN:2046-2069
2046-2069
DOI:10.1039/c9ra09227g