A ratiometric 19 F MR-based method for the quantification of Ca 2+ using responsive paramagnetic probes
We present a method for assessing the extracellular calcium concentration using F chemical shift imaging. Specifically, a custom made calcium-responsive and lanthanide-based F MRI probe that undergoes a strong and highly specific modulation of its signal upon coordination with calcium ions was devel...
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| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2020-03, Vol.56 (24), p.3492-3495 |
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| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | We present a method for assessing the extracellular calcium concentration using
F chemical shift imaging. Specifically, a custom made calcium-responsive and lanthanide-based
F MRI probe that undergoes a strong and highly specific modulation of its signal upon coordination with calcium ions was developed and its performance is presented. |
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| ISSN: | 1359-7345 1364-548X |
| DOI: | 10.1039/c9cc09977h |