Rhodium-catalyzed asymmetric addition of arylboronic acids to 2 H -chromenes leading to 3-arylchromane derivatives

Asymmetric addition of arylboronic acids to 2 H -chromenes proceeded in the presence of a hydroxorhodium/chiral diene catalyst to give 3-arylchromanes in high yields with high enantioselectivity. The reaction involves 1,4-Rh shift before protonation to release the addition product and to regenerate the hydroxorhodium species.