Reductive stress imaging in the endoplasmic reticulum by using living cells and zebrafish

Excessive accumulation of reducing agents in the ER leads to a constitutively high UPR. And the co-function of GSH , Cys and HOCl in biological processes is not well understood. To address this, a TP probe, NPCC , was developed for monitoring reductive stress in the ER. It can also distinguish cancer cells from normal cells. A TP probe, NPCC , was developed for monitoring reductive stress in the ER. It can also distinguish cancer cells from normal cells.