Morphological diversity of supramolecular polymers of DNA-containing oligopyrenes - formation of chiroptically active nanosheets

The effect of DNA on the morphology of supramolecular polymers assembled from chimeric DNA-pyrene oligophosphodiesters in water is described. The number of deoxynucleotides determines if the self-assembly yields 1D or 2D structures. A single guanosine nucleotide attached to a heptapyrenotide induces chiroptical activity in self-assembled nanosheets. Supramolecular polymerization of chimeric DNA-pyrene oligomers leads to 1D and 2D objects depending on the length of the DNA. A single guanosine induces supramolecular chirality in the self-assembled nanosheets.