One-pot synthesis of CuFeO 2 nanoparticles capped with glycerol and proteomic analysis of their nanocytotoxicity against fungi

One-pot synthesis of cuprous ferrite (CuFeO 2 ) nanoparticles modified with glycerol (glycerol@CuFeO 2 NPs) using oligol and reducing agent was reported. The antifungal activities of the nanoparticles for Candida utilis using matrix assisted laser desorption/ionization mass spectrometry (MALDI-MS) a...

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Veröffentlicht in:RSC advances 2016, Vol.6 (100), p.97629-97635
Hauptverfasser: Abdelhamid, Hani Nasser, Kumaran, Sekar, Wu, Hui-Fen
Format: Artikel
Sprache:eng
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Zusammenfassung:One-pot synthesis of cuprous ferrite (CuFeO 2 ) nanoparticles modified with glycerol (glycerol@CuFeO 2 NPs) using oligol and reducing agent was reported. The antifungal activities of the nanoparticles for Candida utilis using matrix assisted laser desorption/ionization mass spectrometry (MALDI-MS) are also reported. Glycerol@CuFeO 2 NPs are synthesized via hydrothermal method and characterized using TEM, SEM, EDX, XRD, FTIR, DLS, and zeta potential. The data revealed that glycerol@CuFeO 2 NPs show an efficient ability to degrade contaminants, such as fungi in the aquatic environment. The proteomic analysis of the pathogenic fungus upon addition of different concentrations of glycerol@CuFeO 2 NPs and different incubation times reveals the degradation of high molecular weight protein to small proteins or peptides.
ISSN:2046-2069
2046-2069
DOI:10.1039/C6RA13396G