Optical properties of porcine dermis in the mid-infrared absorption band of glucose

The optical properties of skin in the mid-infrared range are not known, despite their importance for e.g. non-invasive glucose monitoring. In this paper, transmission, absorption, scattering, and reduced scattering coefficients are quantified using a custom-built goniometer based on a quantum cascad...

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Veröffentlicht in:Analyst (London) 2017-04, Vol.142 (8), p.1235-1243
Hauptverfasser: Schönhals, Arthur, Tholl, Hans, Glasmacher, Mathias, Kröger-Lui, Niels, Pucci, Annemarie, Petrich, Wolfgang
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Sprache:eng
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Zusammenfassung:The optical properties of skin in the mid-infrared range are not known, despite their importance for e.g. non-invasive glucose monitoring. In this paper, transmission, absorption, scattering, and reduced scattering coefficients are quantified using a custom-built goniometer based on a quantum cascade laser operated at the glucose absorption band at a wavelength of around 9.7 μm. The measurements show a strong dominance of absorption and moderate contributions from scattering. The scattered radiation is dominated by single scattering events in the forward direction ( g = 0.967) within the range of the investigated dermis layer thicknesses of up to 50 μm, whereby the fraction of multiple scattering is expected to increase with the layer thickness. Mid-infrared absorption and scattering properties of porcine dermis are quantified using quantum cascade laser-based goniometry.
ISSN:0003-2654
1364-5528
DOI:10.1039/c6an01757f