Dendritic maleimide functionalization of core–shell (γ-Fe 2 O 3 /polymer) nanoparticles for efficient bio-immobilization

Dendritic maleimide functionalization of core–shell (γ-Fe 2 O 3 /polymer) nanoparticles for efficient bio-immobilization

A new route for the preparation of stable and water-dispersible core–shell γ-Fe 2 O 3 /polymer MNPs has been developed in order to ensure a selective and covalent immobilization of biomolecules using maleimide–thiol coupling chemistry. A high maleimide functionalization was achieved by the grafting...

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Veröffentlicht in:RSC advances 2015, Vol.5 (108), p.88574-88577
Hauptverfasser: Mitcova, L., Rahma, H., Buffeteau, T., Clérac, R., Vellutini, L., Heuzé, K.
Format: Artikel
Sprache:eng
Schlagworte:
Chemical Sciences
Material chemistry
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Zusammenfassung:A new route for the preparation of stable and water-dispersible core–shell γ-Fe 2 O 3 /polymer MNPs has been developed in order to ensure a selective and covalent immobilization of biomolecules using maleimide–thiol coupling chemistry. A high maleimide functionalization was achieved by the grafting of dendritic coupling agent via a convergent approach.
ISSN:2046-2069
2046-2069
DOI:10.1039/C5RA17928A