On-bead screening of a library to detect host-guest complexation by an aniline reporter

On-bead screening of a library to detect host-guest complexation by an aniline reporter

We developed a new labeling reagent and a color assay system in water to detect binding between target molecules and library members on beads, which is free of label-induced artifacts that can cause misleading results.

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Bibliographische Detailangaben
Veröffentlicht in:Chemical communications (Cambridge, England) England), 2006-01 (32), p.3390-3392
Hauptverfasser: Kubo, Miwa, Nishimoto, Ryosuke, Doi, Masanori, Kodama, Mitsuaki, Hioki, Hideaki
Format: Artikel
Sprache:eng
Schlagworte:
Aniline Compounds - chemistry
Coloring Agents - chemistry
Microspheres
Molecular Structure
Particle Size
Peptide Library
Peptides - chemistry
Sensitivity and Specificity
Stereoisomerism
Time Factors
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Beschreibung
Zusammenfassung:We developed a new labeling reagent and a color assay system in water to detect binding between target molecules and library members on beads, which is free of label-induced artifacts that can cause misleading results.
ISSN:1359-7345
1364-548X
DOI:10.1039/b604723h