Leptin concentration in newborns' cord blood : relationship to gender and growth-regulating hormones

To verify if plasma leptin concentrations of newborns at birth differ significantly between sexes; and to investigate the potential interactions between plasma leptin and growth-regulating hormones at birth. 98 healthy newborns (48 male, 50 female) were studied. Leptin, insulin, cortisol, insulin-li...

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Veröffentlicht in:	International Journal of Obesity 1999-09, Vol.23 (9), p.943-947
Hauptverfasser:	MAFFEIS, C, MOGHETTI, P, VETTOR, R, LOMBARDI, A. M, VECCHINI, S, TATO, L
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Female Fetal Blood - chemistry Functional investigation of endocrine glands and genital system Humans Hydrocortisone - blood Infant, Newborn Insulin - blood Insulin-Like Growth Factor I - analysis Investigative techniques, diagnostic techniques (general aspects) Leptin - analysis Male Medical sciences Reference Values Regression Analysis Sex Characteristics Sex Hormone-Binding Globulin - analysis Testosterone - blood
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Zusammenfassung:	To verify if plasma leptin concentrations of newborns at birth differ significantly between sexes; and to investigate the potential interactions between plasma leptin and growth-regulating hormones at birth. 98 healthy newborns (48 male, 50 female) were studied. Leptin, insulin, cortisol, insulin-like growth factor-1 (IGF-1), testosterone, and sex hormone binding globulin (SHBG) concentrations were measured from venous blood collected from the umbilical cord vein immediately after birth. The serum leptin concentration of newborns averaged 8.05(0.5) ng/ml. Females had significantly (P
ISSN:	0307-0565 1476-5497
DOI:	10.1038/sj.ijo.0801023