Fatty acids fuelling astroglia and beyond

Fatty acids fuelling astroglia and beyond

Astrocytes are usually viewed as archetypical glycolytic cells. A study now shows that fatty acid oxidation in astrocytes rearranges the respiratory chain to a configuration that safeguards neuronal functionality and proper cognitive performance in mice.

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Veröffentlicht in:Nature metabolism 2023-08, Vol.5 (8), p.1253-1254
1. Verfasser: Guzmán, Manuel
Format: Artikel
Sprache:eng
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Biomedical and Life Sciences
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Zusammenfassung:Astrocytes are usually viewed as archetypical glycolytic cells. A study now shows that fatty acid oxidation in astrocytes rearranges the respiratory chain to a configuration that safeguards neuronal functionality and proper cognitive performance in mice.
ISSN:2522-5812
2522-5812
DOI:10.1038/s42255-023-00845-4