Ferric carboxymaltose for anemia in late pregnancy: a randomized controlled trial

Over 46% of African pregnant women are anemic. Oral iron is recommended but often suboptimal, particularly late in pregnancy. Intravenous ferric carboxymaltose (FCM) could treat anemia in women in the third trimester in sub-Saharan Africa. In an open-label, individually randomized trial in antenatal...

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Veröffentlicht in:Nature medicine 2025-01
Hauptverfasser: Pasricha, Sant-Rayn, Moya, Ernest, Ataíde, Ricardo, Mzembe, Glory, Harding, Rebecca, Mwangi, Martin N., Zinenani, Truwah, Prang, Khic-Houy, Kaunda, Justina, Mtambo, Owen P. L., Vokhiwa, Maclean, Mhango, Gomezgani, Mamani-Mategula, Elisabeth, Fielding, Katherine, Demir, Ayşe, Von Dinklage, Naomi, Verhoef, Hans, McLean, Alistair RD, Manda-Taylor, Lucinda, Braat, Sabine, Phiri, Kamija S.
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Sprache:eng
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Zusammenfassung:Over 46% of African pregnant women are anemic. Oral iron is recommended but often suboptimal, particularly late in pregnancy. Intravenous ferric carboxymaltose (FCM) could treat anemia in women in the third trimester in sub-Saharan Africa. In an open-label, individually randomized trial in antenatal clinics in southern Malawi, we randomized 590 women at 27–35 weeks of gestation with capillary hemoglobin
ISSN:1078-8956
1546-170X
DOI:10.1038/s41591-024-03385-w