Venovenous versus venoarterial extracorporeal membrane oxygenation among infants with hypoxic-ischemic encephalopathy: is there a difference in outcome?

Venovenous versus venoarterial extracorporeal membrane oxygenation among infants with hypoxic-ischemic encephalopathy: is there a difference in outcome?

Objective Our hypothesis was that among infants with hypoxic-ischemic encephalopathy (HIE), venoarterial (VA), compared to venovenous (VV), extracorporeal membrane oxygenation (ECMO) is associated with an increased risk of mortality or intracranial hemorrhage (ICH). Design/methods Retrospective coho...

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Veröffentlicht in:Journal of perinatology 2021-08, Vol.41 (8), p.1916-1923
Hauptverfasser: Agarwal, Prashant, Natarajan, Girija, Sullivan, Kevin, Rao, Rakesh, Rintoul, Natalie, Zaniletti, Isabella, Keene, Sarah, Mietzsch, Ulrike, Massaro, An N., Billimoria, Zeenia, Dirnberger, Daniel, Hamrick, Shannon, Seabrook, Ruth B., Weems, Mark F., Cleary, John P., Gray, Brian W., DiGeronimo, Robert
Format: Artikel
Sprache:eng
Schlagworte:
692/308/409
692/699/1785
Blood oxygenation, Extracorporeal
Brain
Brain damage
Child
Cohort Studies
Diseases
Encephalopathy
Extracorporeal Membrane Oxygenation
Gestational age
Hemorrhage
Humans
Hypoxia
Hypoxia-Ischemia, Brain - therapy
Infant
Infant, Newborn
Infants
Infants (Newborn)
Intracranial Hemorrhages
Ischemia
Life Sciences & Biomedicine
Medicine
Medicine & Public Health
Membranes
Mortality
Neonates
Obstetrics & Gynecology
Oxygenation
Patient outcomes
Pediatric Surgery
Pediatrics
Retrospective Studies
Risk factors
Science & Technology
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Zusammenfassung:Objective Our hypothesis was that among infants with hypoxic-ischemic encephalopathy (HIE), venoarterial (VA), compared to venovenous (VV), extracorporeal membrane oxygenation (ECMO) is associated with an increased risk of mortality or intracranial hemorrhage (ICH). Design/methods Retrospective cohort analysis of infants in the Children’s Hospitals Neonatal Database from 2010 to 2016 with moderate or severe HIE, gestational age ≥36 weeks, and ECMO initiation
ISSN:0743-8346
1476-5543
DOI:10.1038/s41372-021-01089-4