Fetal Haemodinamic and Neonatal Cerebral Circulation in Maternal Threatened Preterm Labor

Background and aims: The improvement of practical approach to cerebral hemodynamic disturbances in neonates starting from fetal period is important for prevent of hypoxic encephalopathy. Methods: Prospective investigation of fetal and cerebral neonatal circulation was preformed on 36 neonates: I group - 13 infants with physiologic course maternal pregnancy and 20 ones - with maternal threatened preterm labor. Mean age of fetal circulation investigation was 34.1±4.0 weeks. Results: The statistically significant difference (Mann-Whitney U Test) were at medial cerebral artery (MCA): V max 47 cm/s (I) and 42.8 cm/s (II) [?=0.022]; Vmin 15.8 cm/s (I) and 12.6 cm/s (II) [?=0,000]. After birth in II group infants the resistance index (RI) in MCA was high 0.68(I) and 0.73(II) [?=0,008]. The nonparametric Spearman correlation for highlighting p-level < 0.05 has shown a positive relation between V max umbilical artery and Vmin, V max , and IR in MCA in neonate (R=0.34). Conclusions: We conclude that infants with maternal threatened preterm labor mothers have decreasing of cerebral hemodynamic speeds since intrauterine period. There is a relation between umbilical flow and cerebral circulation before and after birth.