Loaded-up microsponges

Self-assembled microsponges of hairpin RNA polymers achieve, with one thousand times lower concentration, the same degree of gene silencing in tumour-carrying mice as conventional nanoparticle-based siRNA delivery vehicles.

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Bibliographische Detailangaben
Veröffentlicht in:	Nature materials 2012-03, Vol.11 (4), p.268-269
Hauptverfasser:	Grabow, Wade W., Jaeger, Luc
Format:	Artikel
Sprache:	eng
Schlagworte:	631/61/391/505 639/301/54/992 Biomaterials Chemistry and Materials Science Condensed Matter Physics Materials Science Nanotechnology news-and-views Optical and Electronic Materials
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Self-assembled microsponges of hairpin RNA polymers achieve, with one thousand times lower concentration, the same degree of gene silencing in tumour-carrying mice as conventional nanoparticle-based siRNA delivery vehicles.
ISSN:	1476-1122 1476-4660
DOI:	10.1038/nmat3286