Epigenetics: A New Link Toward Understanding Human Disease and Drug Response

Molecular medicine is moving beyond genomics to encompass the new scientific field of epigenetics. First described as a conceptual model of how genes might interact with their surroundings to produce a phenotype, epigenomic research currently investigates mechanisms of nongenetic modification contri...

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Veröffentlicht in:	Clinical pharmacology and therapeutics 2012-12, Vol.92 (6), p.669-673
Hauptverfasser:	Cressman, A M, Piquette-Miller, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Disease - genetics Drug Discovery Epigenesis, Genetic - physiology Epigenomics - trends Gene-Environment Interaction Humans Pharmacology - methods
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Molecular medicine is moving beyond genomics to encompass the new scientific field of epigenetics. First described as a conceptual model of how genes might interact with their surroundings to produce a phenotype, epigenomic research currently investigates mechanisms of nongenetic modification contributing to gene regulation and examines the impact of these changes on human health and behavior. Clinical Pharmacology & Therapeutics (2012); 92 6, 669–673. doi:10.1038/clpt.2012.179
ISSN:	0009-9236 1532-6535
DOI:	10.1038/clpt.2012.179