Corrections in the catalogue of oligonucleotides produced by digestion of Escherichia coli 16S rRNA with T1 RNase

SINCE its initial publication 1 , the catalogue of oligonucleotides generated by T1 RNase digestion of Escherichia coli 16S RNA has undergone a number of revisions and refinements 2–5 . At present the literature contains two rather dissimilar documented versions of this catalogue 2,3 and disagreements hold for 50% of sequences octamer and larger 3 . Confusion is not relieved by recent publications concerning the 16SrRNA primary structure 6,7 that now incorporate some of the oligomer sequences of Uchida et al. 3 but reject others, without resort to new evidence, however.