Antitumour Effect of Lymphoid Cells activated by Interferon

Antitumour Effect of Lymphoid Cells activated by Interferon

INTERFERON induces a cytotoxic effect in normal mouse spleen cells against allogeneic tumour target cells in tissue culture 1,2 . We here present evidence that syngeneic lymphoid cells may be similarly activated by interferon and that syngeneic lymphoid cells plus interferon suppress the growth of t...

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Veröffentlicht in:Nature (London) 1970-10, Vol.228 (5266), p.71-72
Hauptverfasser: CHERNYAKHOVSKAYA, INESSA YU, SLAVINA, ELENA G, SVET-MOLDAVSKY, GEORGE J
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Benz(a)Anthracenes
Humanities and Social Sciences
In Vitro Techniques
Interferons - toxicity
L Cells (Cell Line) - immunology
letter
Lymphocytes - immunology
Mice
multidisciplinary
Neoplasm Transplantation
Sarcoma, Experimental - chemically induced
Sarcoma, Experimental - immunology
Science
Science (multidisciplinary)
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Zusammenfassung:INTERFERON induces a cytotoxic effect in normal mouse spleen cells against allogeneic tumour target cells in tissue culture 1,2 . We here present evidence that syngeneic lymphoid cells may be similarly activated by interferon and that syngeneic lymphoid cells plus interferon suppress the growth of tumour cells in vivo .
ISSN:0028-0836
1476-4687
DOI:10.1038/228071a0