Tetanus Toxin, a Neuromuscular Blocking Agent

Tetanus Toxin, a Neuromuscular Blocking Agent

IN some cases of infectious tetanus a neuromuscular block with tetraplegia may follow the state of muscle spasms. We suggested 1 that this effect was caused by the tetanus toxin itself rather than to an after-effect of muscle relaxants or other drugs. This hypothesis, however, had to be verified by...

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Veröffentlicht in:Nature (London) 1969-08, Vol.223 (5208), p.842-842
Hauptverfasser: KAESER, H. E, SANER, A
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Humanities and Social Sciences
letter
Magnesium Sulfate - pharmacology
multidisciplinary
Muscle Contraction - drug effects
Neuromuscular Junction - drug effects
Rats
Science
Science (multidisciplinary)
Succinylcholine - pharmacology
Tetanus Toxin - pharmacology
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Zusammenfassung:IN some cases of infectious tetanus a neuromuscular block with tetraplegia may follow the state of muscle spasms. We suggested 1 that this effect was caused by the tetanus toxin itself rather than to an after-effect of muscle relaxants or other drugs. This hypothesis, however, had to be verified by experiments with animals.
ISSN:0028-0836
1476-4687
DOI:10.1038/223842a0