Effect of Cell Cycle on Recovery from Radiation Damage in the Mouse Liver

I HAVE studied the chromosomal aberrations which are induced in mouse hepatocytes by single and fractionated doses of X-rays given at various times before or after surgical partial hepatectomy. The data presented here show that the different phases of the cell cycle possibly differ not only in their...

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Veröffentlicht in:	Nature (London) 1968-01, Vol.217 (5124), p.180-182
1. Verfasser:	COGGLE, J. E
Format:	Artikel
Sprache:	eng
Schlagworte:	ANIMAL CELLS Animals Autoradiography CHROMOSOMES Chromosomes - radiation effects CHROMOSOMES/radioinduced aberrations of, in liver of mice, effects of cell cycle hepatectomy on recovery from x Female Hepatectomy Humanities and Social Sciences letter LIVER Liver - cytology Liver - radiation effects Liver Regeneration LIVER/radioinduced chromosome aberrations in, of mice, effects of cell cycle on recovery from x MICE MICE/radioinduced chromosome aberrations in liver of, effects of cell cycle on recovery from x Mitosis - radiation effects multidisciplinary N28300 -Life Sciences-Genetics & Cytogenetics RADIATION EFFECTS RADIATION INJURIES RECOVERY Science SURGERY X RADIATION X RADIATION/ effects on chromosomes in liver of mice, effects of cell cycle on recovery from aberrant
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Zusammenfassung:	I HAVE studied the chromosomal aberrations which are induced in mouse hepatocytes by single and fractionated doses of X-rays given at various times before or after surgical partial hepatectomy. The data presented here show that the different phases of the cell cycle possibly differ not only in their sensitivity to chromosomal damage by radiation but also in their ability to recover from such damage.
ISSN:	0028-0836 1476-4687
DOI:	10.1038/217180a0