Lymphocytes in Congenital Absence of the Thymus

Lymphocytes in Congenital Absence of the Thymus

Lymphocytes of presumably extrathymic origin were obtained from an immunologically deficient child in whom there was complete failure of development of the thymus. They were poorly responsive to phytohaemagglutinin and to antigens, and responsiveness was not induced by incubation with thymic or tran...

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Veröffentlicht in:Nature (London) 1967-05, Vol.214 (5088), p.580-582
Hauptverfasser: LISCHNER, HAROLD W, PUNNETT, HOPE H, DiGEORGE, ANGELO M
Format: Artikel
Sprache:eng
Schlagworte:
Humanities and Social Sciences
multidisciplinary
Science
Science (multidisciplinary)
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Zusammenfassung:Lymphocytes of presumably extrathymic origin were obtained from an immunologically deficient child in whom there was complete failure of development of the thymus. They were poorly responsive to phytohaemagglutinin and to antigens, and responsiveness was not induced by incubation with thymic or transfer factors.
ISSN:0028-0836
1476-4687
DOI:10.1038/214580a0