Effect of Calcium on Mitosis in the Thymuses of Normal and Irradiated Rats

THE demonstration that increased levels of calcium in cultures of strain L mouse fibroblasts and rat thymocytes stimulated mitosis and reduced, or prevented, the transient mitotic delay produced by irradiation 1,2 led to the hypothesis that a rise in the concentration of calcium in the blood and tis...

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Veröffentlicht in:	Nature (London) 1967-04, Vol.214 (5085), p.302-303
Hauptverfasser:	WHITFIELD, J. F, PERRIS, A. D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CALCIUM Calcium - pharmacology Cell Division - drug effects Colchicine - pharmacology GAMMA RADIATION Humanities and Social Sciences letter MITOSIS multidisciplinary N28620 -Life Sciences-Radiation Effects on Animals- Vertebrates RADIATION DOSES Radiation Effects RADIATION INJURIES RATS RECOVERY Science Science (multidisciplinary) THYMUS Thymus Gland - growth & development Thymus Gland - radiation effects TIME
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Beschreibung
Zusammenfassung:	THE demonstration that increased levels of calcium in cultures of strain L mouse fibroblasts and rat thymocytes stimulated mitosis and reduced, or prevented, the transient mitotic delay produced by irradiation 1,2 led to the hypothesis that a rise in the concentration of calcium in the blood and tissues might also stimulate normal mitosis and reduce post-irradiation mitotic delay in the whole animal.
ISSN:	0028-0836 1476-4687
DOI:	10.1038/214302a0