Antiviral Activity of Gliotoxin and Gliotoxin Acetate
DURING a search for antiviral materials, we found several Penicillium culture filtrates that inhibited the cytopathic effect of type 2 poliovirus MEF 1 in monkey kidney primary cell cultures. The antipolio activity of these filtrates was found to be due to gliotoxin and gliotoxin acetate.
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| Veröffentlicht in: | Nature (London) 1964-12, Vol.204 (4965), p.1333-1334 |
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| container_end_page | 1334 |
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| container_issue | 4965 |
| container_start_page | 1333 |
| container_title | Nature (London) |
| container_volume | 204 |
| creator | RIGHTSEL, WILTON A SCHNEIDER, HORST G SLOAN, BERNARD J GRAF, PERSIS R MILLER, FRANCIS A BARTZ, QUENTIN R EHRLICH, JOHN DIXON, GLEN J |
| description | DURING a search for antiviral materials, we found several
Penicillium
culture filtrates that inhibited the cytopathic effect of type 2 poliovirus
MEF
1
in monkey kidney primary cell cultures. The antipolio activity of these filtrates was found to be due to gliotoxin and gliotoxin acetate. |
| doi_str_mv | 10.1038/2041333b0 |
| format | Article |
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Penicillium
culture filtrates that inhibited the cytopathic effect of type 2 poliovirus
MEF
1
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Penicillium
culture filtrates that inhibited the cytopathic effect of type 2 poliovirus
MEF
1
in monkey kidney primary cell cultures. The antipolio activity of these filtrates was found to be due to gliotoxin and gliotoxin acetate.</description><subject>Acetates</subject><subject>Animals</subject><subject>Antitoxins</subject><subject>Antiviral Agents</subject><subject>Enterovirus</subject><subject>Enterovirus B, Human</subject><subject>Gliotoxin</subject><subject>Humanities and Social Sciences</subject><subject>letter</subject><subject>Measles virus</subject><subject>Mice</subject><subject>multidisciplinary</subject><subject>Orthomyxoviridae</subject><subject>Paramyxoviridae Infections</subject><subject>Penicillium</subject><subject>Poliovirus</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><subject>Simplexvirus</subject><subject>Toxicology</subject><subject>Toxins, Biological</subject><subject>Vaccinia virus</subject><issn>0028-0836</issn><issn>1476-4687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1964</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptz0FLwzAUB_AgipvTg19Ae1WoviQvTXMsQ6cw8KLnkqSJdGztSDNx334dHZsHT3nh_fjz_oTcUniiwPNnBkg55wbOyJiizFLMcnlOxgAsTyHn2Yhcdd0CAASVeElGFJlARBgTUTSx_qmDXiaF3U9xm7Q-mS3rNra_dZPopvrzK6yLOrprcuH1snM3h3dCvl5fPqdv6fxj9j4t5qnlyGKqpAJhFDXUO6a8zSijCEayqqLOeE7RW8eVRJsZoaxQwKxA7iRW3moPfEIehlwb2q4LzpfrUK902JYUyn318li9t3eDXW_MylUneejag8cBdP2q-XahXLSb0PT3_5t2P-BGx01wx7ST2AFm4Go0</recordid><startdate>19641226</startdate><enddate>19641226</enddate><creator>RIGHTSEL, WILTON A</creator><creator>SCHNEIDER, HORST G</creator><creator>SLOAN, BERNARD J</creator><creator>GRAF, PERSIS R</creator><creator>MILLER, FRANCIS A</creator><creator>BARTZ, QUENTIN R</creator><creator>EHRLICH, JOHN</creator><creator>DIXON, GLEN J</creator><general>Nature Publishing Group UK</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19641226</creationdate><title>Antiviral Activity of Gliotoxin and Gliotoxin Acetate</title><author>RIGHTSEL, WILTON A ; SCHNEIDER, HORST G ; SLOAN, BERNARD J ; GRAF, PERSIS R ; MILLER, FRANCIS A ; BARTZ, QUENTIN R ; EHRLICH, JOHN ; DIXON, GLEN J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c342t-97905b91b1fe29fc612140b72dd1ebf314fce3974c6b59c5902c543e74dfcaf03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1964</creationdate><topic>Acetates</topic><topic>Animals</topic><topic>Antitoxins</topic><topic>Antiviral Agents</topic><topic>Enterovirus</topic><topic>Enterovirus B, Human</topic><topic>Gliotoxin</topic><topic>Humanities and Social Sciences</topic><topic>letter</topic><topic>Measles virus</topic><topic>Mice</topic><topic>multidisciplinary</topic><topic>Orthomyxoviridae</topic><topic>Paramyxoviridae Infections</topic><topic>Penicillium</topic><topic>Poliovirus</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><topic>Simplexvirus</topic><topic>Toxicology</topic><topic>Toxins, Biological</topic><topic>Vaccinia virus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>RIGHTSEL, WILTON A</creatorcontrib><creatorcontrib>SCHNEIDER, HORST G</creatorcontrib><creatorcontrib>SLOAN, BERNARD J</creatorcontrib><creatorcontrib>GRAF, PERSIS R</creatorcontrib><creatorcontrib>MILLER, FRANCIS A</creatorcontrib><creatorcontrib>BARTZ, QUENTIN R</creatorcontrib><creatorcontrib>EHRLICH, JOHN</creatorcontrib><creatorcontrib>DIXON, GLEN J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Nature (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>RIGHTSEL, WILTON A</au><au>SCHNEIDER, HORST G</au><au>SLOAN, BERNARD J</au><au>GRAF, PERSIS R</au><au>MILLER, FRANCIS A</au><au>BARTZ, QUENTIN R</au><au>EHRLICH, JOHN</au><au>DIXON, GLEN J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antiviral Activity of Gliotoxin and Gliotoxin Acetate</atitle><jtitle>Nature (London)</jtitle><stitle>Nature</stitle><addtitle>Nature</addtitle><date>1964-12-26</date><risdate>1964</risdate><volume>204</volume><issue>4965</issue><spage>1333</spage><epage>1334</epage><pages>1333-1334</pages><issn>0028-0836</issn><eissn>1476-4687</eissn><abstract>DURING a search for antiviral materials, we found several
Penicillium
culture filtrates that inhibited the cytopathic effect of type 2 poliovirus
MEF
1
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| fulltext | fulltext |
| identifier | ISSN: 0028-0836 |
| ispartof | Nature (London), 1964-12, Vol.204 (4965), p.1333-1334 |
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| source | MEDLINE; Nature; Alma/SFX Local Collection |
| subjects | Acetates Animals Antitoxins Antiviral Agents Enterovirus Enterovirus B, Human Gliotoxin Humanities and Social Sciences letter Measles virus Mice multidisciplinary Orthomyxoviridae Paramyxoviridae Infections Penicillium Poliovirus Science Science (multidisciplinary) Simplexvirus Toxicology Toxins, Biological Vaccinia virus |
| title | Antiviral Activity of Gliotoxin and Gliotoxin Acetate |
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