Structure of the Carbohydrate Moiety of Orosomucoid

OROSOMUCOID isolated from serum has been the subject of many investigations in recent years 1–4 . Popenoe 5 isolated an α 1 -glycoprotein from the urine of patients with the nephrotic syndrome and showed it to be immunochemically identical to serum orosomucoid. More recently the glycoprotein has been isolated from the same source by means of cellulose ion-exchangers 6 . This glycoprotein was shown also to be identical to serum orosomucoid by immuno-electrophoresis and gel-diffusion techniques, and was found to be homogeneous by physical and chemical techniques 7 .