Cobalt as a Carcinogen

THE effects of various metals on living cells in tissue culture are being investigated in this Laboratory, and a non-lethal disturbance of normal mitosis produced in chick fibroblasts by cobalt (as chloride) has already been reported 1 . This effect, which is characterized by the persistence of the...

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Veröffentlicht in:	Nature 1954-05, Vol.173 (4409), p.822-823
1. Verfasser:	HEATH, J. C.
Format:	Artikel
Sprache:	eng
Schlagworte:	BIOLOGY AND MEDICINE BIRDS CANCER CARCINOGENESIS Carcinogens Cobalt - pharmacology COBALT CHLORIDES Humanities and Social Sciences Humans letter MITOSIS multidisciplinary MUSCLES RADIATION INJURIES RATS Science Science (multidisciplinary) SOLUTIONS
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Beschreibung
Zusammenfassung:	THE effects of various metals on living cells in tissue culture are being investigated in this Laboratory, and a non-lethal disturbance of normal mitosis produced in chick fibroblasts by cobalt (as chloride) has already been reported 1 . This effect, which is characterized by the persistence of the nucleoli in mitotic cells throughout prophase into meta-, ana- and telo-phase, appears to be specific for cobalt, inasmuch as no comparable effect is produced by nickel, iron, zinc, chromium, manganese or beryllium in sublethal concentrations.
ISSN:	0028-0836 1476-4687
DOI:	10.1038/173822a0