Efficient Large Scale Synthesis of 2‘-O-Alkyl Pyrimidine Ribonucleosides

Efficient Large Scale Synthesis of 2‘-O-Alkyl Pyrimidine Ribonucleosides

An efficient process to synthesize 2‘-O-alkyl pyrimidine ribonucleosides in high yield has been described. The inexpensive method was used on a multikilogram-scale synthesis and optimized reaction conditions have been investigated.

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Veröffentlicht in:Organic process research & development 2000-05, Vol.4 (3), p.170-171
Hauptverfasser: Roy, Saroj K, Tang, Jin-yan
Format: Artikel
Sprache:eng
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Zusammenfassung:An efficient process to synthesize 2‘-O-alkyl pyrimidine ribonucleosides in high yield has been described. The inexpensive method was used on a multikilogram-scale synthesis and optimized reaction conditions have been investigated.
ISSN:1083-6160
1520-586X
DOI:10.1021/op990100t