Process Research and Structural Studies on Nabumetone

A short, simple and economical process for large-scale preparation of nabumetone has been developed. The single-crystal structures of nabumetone and one of its key intermediates have been determined by X-ray diffraction studies. Two impurities have been isolated and characterised.

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Veröffentlicht in:Organic process research & development 1999-03, Vol.3 (2), p.121-125
Hauptverfasser: Prabhakar, C, Reddy, G. Bakki, Reddy, Ch. Maheedhara, Nageshwar, D, Devi, A. Sivalakshmi, Babu, J. Moses, Vyas, K, Sarma, M. R, Reddy, G. Om
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Sprache:eng
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Zusammenfassung:A short, simple and economical process for large-scale preparation of nabumetone has been developed. The single-crystal structures of nabumetone and one of its key intermediates have been determined by X-ray diffraction studies. Two impurities have been isolated and characterised.
ISSN:1083-6160
1520-586X
DOI:10.1021/op980060d