Scale-Up of an Intermolecular Barbier Reaction

Scale-Up of an Intermolecular Barbier Reaction

Addition of n-BuLi to a mixture of ketone (2) and 1,4-diiodobenzene provides access to alcohol (1) in high yield. This procedure has successfully been used on molar scale.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Organic process research & development 1998-09, Vol.2 (5), p.287-289
Hauptverfasser: Ennis, David S, Lathbury, David C, Wanders, Andre, Watts, David
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Addition of n-BuLi to a mixture of ketone (2) and 1,4-diiodobenzene provides access to alcohol (1) in high yield. This procedure has successfully been used on molar scale.
ISSN:1083-6160
1520-586X
DOI:10.1021/op980003k