An Improved and Scalable Process for Zafirlukast: An Asthma Drug

An Improved and Scalable Process for Zafirlukast: An Asthma Drug

An improved and scalable process for the large-scale production of zafirlukast (Accolate), an important drug for asthma, is discussed along with impurity and scale-up-related issues.

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Veröffentlicht in:Organic process research & development 2009-01, Vol.13 (1), p.67-72
Hauptverfasser: Goverdhan, Gilla, Reddy, Anumula Raghupathi, Sampath, Aalla, Srinivas, Kurella, Himabindu, Vurimidi, Reddy, Ghanta Mahesh
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container_end_page 72
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container_title Organic process research & development
container_volume 13
creator Goverdhan, Gilla
Reddy, Anumula Raghupathi
Sampath, Aalla
Srinivas, Kurella
Himabindu, Vurimidi
Reddy, Ghanta Mahesh
description An improved and scalable process for the large-scale production of zafirlukast (Accolate), an important drug for asthma, is discussed along with impurity and scale-up-related issues.
doi_str_mv 10.1021/op800137b
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title An Improved and Scalable Process for Zafirlukast: An Asthma Drug
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