An Improved and Scalable Process for Zafirlukast: An Asthma Drug

An improved and scalable process for the large-scale production of zafirlukast (Accolate), an important drug for asthma, is discussed along with impurity and scale-up-related issues.

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Bibliographische Detailangaben
Veröffentlicht in:	Organic process research & development 2009-01, Vol.13 (1), p.67-72
Hauptverfasser:	Goverdhan, Gilla, Reddy, Anumula Raghupathi, Sampath, Aalla, Srinivas, Kurella, Himabindu, Vurimidi, Reddy, Ghanta Mahesh
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	An improved and scalable process for the large-scale production of zafirlukast (Accolate), an important drug for asthma, is discussed along with impurity and scale-up-related issues.
ISSN:	1083-6160 1520-586X
DOI:	10.1021/op800137b