Process Development for the Sulfonamide Herbicide Pyroxsulam
The development of a manufacturing process for the initial commercial production of pyroxsulam sulfonamide herbicide is described. The process encompasses seven reaction steps, and includes a new route to 4-(trifluoromethyl)pyridines, a scaleable method of lithiating a pyridine intermediate, and a s...
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| Veröffentlicht in: | Organic process research & development 2008-03, Vol.12 (2), p.301-303 |
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| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | The development of a manufacturing process for the initial commercial production of pyroxsulam sulfonamide herbicide is described. The process encompasses seven reaction steps, and includes a new route to 4-(trifluoromethyl)pyridines, a scaleable method of lithiating a pyridine intermediate, and a sulfilimine-catalyzed formation of a sulfonamide. |
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| ISSN: | 1083-6160 1520-586X |
| DOI: | 10.1021/op700281w |