Kinetics and Process Development for Deoxofluorination of a Steroid

In this paper investigations for developing a continuous process for the fluorination of a steroid derivative with bis(methoxyethyl)-aminosulfurtrifluoride are presented. A kinetic model is suggested for this reaction. A simulation-based experimental design approach was implemented to find the optim...

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Veröffentlicht in:	Organic process research & development 2008-03, Vol.12 (2), p.345-348
Hauptverfasser:	Negi, Devender S, Köppling, Lars, Lovis, Kai, Abdallah, Radwan, Geisler, Jens, Budde, Uwe
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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