Synthesis of Fluorinated and Nonfluorinated Tebufenpyrad Analogues for the Study of Anti-angiogenesis MOA

Synthesis of Fluorinated and Nonfluorinated Tebufenpyrad Analogues for the Study of Anti-angiogenesis MOA

In this contribution we report the synthesis of fluorinated and nonfluorinated tebufenpyrad analogues to explore potential druglike properties through the phenotypic screening as part of the Lilly Open Innovation Drug Discovery (OIDD) program.

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Veröffentlicht in:Organic process research & development 2014-08, Vol.18 (8), p.1027-1036
Hauptverfasser: Román, Raquel, Navarro, Antonio, Wodka, Dariusz, Alvim-Gaston, Maria, Husain, Saba, Franklin, Natalie, Simón-Fuentes, Antonio, Fustero, Santos
Format: Artikel
Sprache:eng
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Zusammenfassung:In this contribution we report the synthesis of fluorinated and nonfluorinated tebufenpyrad analogues to explore potential druglike properties through the phenotypic screening as part of the Lilly Open Innovation Drug Discovery (OIDD) program.
ISSN:1083-6160
1520-586X
DOI:10.1021/op500114v