Terpyridine Ruthenium-Catalyzed One-Pot Conversion of Aldehydes into Amides
TerpyRu(PPh3)Cl2 is an efficient catalyst for rearranging aldoximes to amides without the need for chelating phosphines or additives as in prior examples. The catalyst is also useful in converting aldehydes into amides in a one-pot process using NaHCO3 as an additive. A mechanism involving nucleophi...
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| Veröffentlicht in: | Organometallics 2009-02, Vol.28 (3), p.922-924 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | TerpyRu(PPh3)Cl2 is an efficient catalyst for rearranging aldoximes to amides without the need for chelating phosphines or additives as in prior examples. The catalyst is also useful in converting aldehydes into amides in a one-pot process using NaHCO3 as an additive. A mechanism involving nucleophilic attack of deprotonated oxime on an adjacent nitrile is suggested. |
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| ISSN: | 0276-7333 1520-6041 |
| DOI: | 10.1021/om8010678 |