Synthesis of a C-linked Antifreeze Glycoprotein (AFGP) Mimic:  Probes for Investigating the Mechanism of Action

Synthesis of a C-linked Antifreeze Glycoprotein (AFGP) Mimic:  Probes for Investigating the Mechanism of Action

A general convergent synthesis has been developed to afford a low molecular weight C-linked antifreeze glycoprotein (AFGP) mimic (9). Structural mimics of AFGPs have tremendous potential as probes to better understand how native AFGPs inhibit ice crystal growth in organisms that inhabit subzero envi...

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Veröffentlicht in:Organic letters 1999-12, Vol.1 (11), p.1759-1762
Hauptverfasser: Ben, Robert N, Eniade, Adewale A, Hauer, Lisa
Format: Artikel
Sprache:eng
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Zusammenfassung:A general convergent synthesis has been developed to afford a low molecular weight C-linked antifreeze glycoprotein (AFGP) mimic (9). Structural mimics of AFGPs have tremendous potential as probes to better understand how native AFGPs inhibit ice crystal growth in organisms that inhabit subzero environments.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol991025+