Facile Synthesis of (E)-Alkenyl Aldehydes from Allyl Arenes or Alkenes via Pd(II)-Catalyzed Direct Oxygenation of Allylic C−H Bond

Facile Synthesis of (E)-Alkenyl Aldehydes from Allyl Arenes or Alkenes via Pd(II)-Catalyzed Direct Oxygenation of Allylic C−H Bond

Palladium-catalyzed oxygenation of allyl arenes or alkenes has been developed to produce (E)-alkenyl aldehydes with high yields. Allylic C−H bond cleavages occur under the mild conditions during this process. Mechanistic studies show that oxygen source is water.

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Veröffentlicht in:Organic letters 2011-03, Vol.13 (5), p.992-994
Hauptverfasser: Chen, Huoji, Jiang, Huanfeng, Cai, Congbi, Dong, Jia, Fu, Wei
Format: Artikel
Sprache:eng
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Zusammenfassung:Palladium-catalyzed oxygenation of allyl arenes or alkenes has been developed to produce (E)-alkenyl aldehydes with high yields. Allylic C−H bond cleavages occur under the mild conditions during this process. Mechanistic studies show that oxygen source is water.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol1030316