More Kapakahines from the Marine Sponge Cribrochalina o lemda

More Kapakahines from the Marine Sponge Cribrochalina o lemda

Three new kapakahines E−G (1−3) have been isolated from the marine sponge Cribrochalina olemda. Limited quantities of these compounds required not only NMR analysis but also FAB-MS/MS analysis for the structure elucidation. Kapakahine E showed cytotoxicity against P388 murine leukemia cells.

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Veröffentlicht in:Organic letters 2003-05, Vol.5 (9), p.1387-1390
Hauptverfasser: Nakao, Yoichi, Kuo, Jacqueline, Yoshida, Wesley Y, Kelly, Michelle, Scheuer, Paul J
Format: Artikel
Sprache:eng
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Zusammenfassung:Three new kapakahines E−G (1−3) have been isolated from the marine sponge Cribrochalina olemda. Limited quantities of these compounds required not only NMR analysis but also FAB-MS/MS analysis for the structure elucidation. Kapakahine E showed cytotoxicity against P388 murine leukemia cells.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol026830u