Palladium(II)-Mediated Cascade Carbonylative Annulation of o-Alkynyl-phenols on Silyl Linker-Based Macrobeads:  A Combinatorial Synthesis of a 2,3-Disubstituted Benzo[b]furan Library

Palladium(II)-Mediated Cascade Carbonylative Annulation of o-Alkynyl-phenols on Silyl Linker-Based Macrobeads:  A Combinatorial Synthesis of a 2,3-Disubstituted Benzo[b]furan Library

A palladium(II)-mediated cascade carbonylative annulation of o-alkynylphenols was achieved successfully on silyl linker-based macrobeads, which led to an efficient combinatorial synthesis of a 2,3-disubstituted benzo[b]furan library.

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Veröffentlicht in:Organic letters 2002-07, Vol.4 (15), p.2607-2609
Hauptverfasser: Liao, Yun, Reitman, Michael, Zhang, Yan, Fathi, Reza, Yang, Zhen
Format: Artikel
Sprache:eng
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Zusammenfassung:A palladium(II)-mediated cascade carbonylative annulation of o-alkynylphenols was achieved successfully on silyl linker-based macrobeads, which led to an efficient combinatorial synthesis of a 2,3-disubstituted benzo[b]furan library.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol020111y