Lupene-Type Triterpenes from Periploca a phylla

Lupene-Type Triterpenes from Periploca a phylla

Two new lupane derivatives, 3β,6α-dihydroxylup-20(29)-ene (1) and 6α-hydroxylup-20(29)-en-3β-octadecanoate (2), have been isolated from the stems of Periploca aphylla, in addition to β-sitosterol and lupeol. The structures of 1 and 2 were determined by spectral and chemical methods. Compound 1 showe...

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Veröffentlicht in:Journal of natural products (Washington, D.C.) D.C.), 2000-06, Vol.63 (6), p.881-883
Hauptverfasser: Mustafa, Ghulam, Anis, Erum, Ahmed, Saeed, Anis, Itrat, Ahmed, Habib, Malik, Abdul, Shahzad-ul-Hassan, Syed, Choudhary, M. Iqbal
Format: Artikel
Sprache:eng
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Zusammenfassung:Two new lupane derivatives, 3β,6α-dihydroxylup-20(29)-ene (1) and 6α-hydroxylup-20(29)-en-3β-octadecanoate (2), have been isolated from the stems of Periploca aphylla, in addition to β-sitosterol and lupeol. The structures of 1 and 2 were determined by spectral and chemical methods. Compound 1 showed strong inhibition of α-glucosidase type VI and a moderate antibacterial activity.
ISSN:0163-3864
1520-6025
DOI:10.1021/np990426v