cis-Monotetrahydrofuran Acetogenins from the Roots of Annona muricata

Phytochemical investigation of roots of Annona muricata led to the identification of seven mono-tetrahydrofuran (mono-THF) acetogenins. Six new acetogenins having the unusual cis-configuration of the THF ring, cis-solamin (1), cis-panatellin (2), cis-uvariamicin IV (3), cis-uvariamicin I (4), cis-re...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 1998-05, Vol.61 (5), p.576-579
Hauptverfasser:	Gleye, Christophe, Duret, Philippe, Laurens, Alain, Hocquemiller, Reynald, Cavé, André
Format:	Artikel
Sprache:	eng
Schlagworte:	ANNONA MURICATA Biological and medical sciences CHEMICAL COMPOSITION CHEMICAL STRUCTURE CIS-PANATELLIN CIS-RETICULATACIN-10-ONE CIS-SOLAMIN CIS-UVARIAMICIN I CIS-UVARIAMICIN IV COHIBINS COMPOSICION QUIMICA COMPOSITION CHIMIQUE ESPECTROMETRIA ESTRUCTURA QUIMICA FURANE FURANOS FURANS General pharmacology GUANABANA GUINEA GUINEE Medical sciences MONTECRISTIN MURIDIENINS Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments RACINE RAICES ROOTS SOUR-SOP SPECTRAL ANALYSIS SPECTROMETRIE SPECTROMETRY STRUCTURE CHIMIQUE
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Zusammenfassung:	Phytochemical investigation of roots of Annona muricata led to the identification of seven mono-tetrahydrofuran (mono-THF) acetogenins. Six new acetogenins having the unusual cis-configuration of the THF ring, cis-solamin (1), cis-panatellin (2), cis-uvariamicin IV (3), cis-uvariamicin I (4), cis-reticulatacin (5), and cis-reticulatacin-10-one (6) were identified, in addition to a known compound, solamin.
ISSN:	0163-3864 1520-6025
DOI:	10.1021/np970494m