Antifungal Activity of Trillium grandiflorum Constituents

EtOH extracts of the rhizomes and aboveground portion of Trillium grandiflorum showed significant antifungal activity. Bioassay directed fractionation has led to the identification of the active components as the saponin glycosides 1 and 3.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 1988-01, Vol.51 (1), p.94-98
Hauptverfasser:	Hufford, Charles D, Liu, Shihchih, Clark, Alice M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antifungal Agents - pharmacology Antifungal Agents - therapeutic use Antifungal Agents - toxicity Biological and medical sciences Candidiasis - drug therapy COMPOSICION COMPOSITION FONGICIDE Fungi - drug effects FUNGICIDAS FUNGICIDES General pharmacology LILIACEAE Magnetic Resonance Spectroscopy Medical sciences Mice Microbial Sensitivity Tests Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Extracts - pharmacology Plant Extracts - therapeutic use Plant Extracts - toxicity Plants, Medicinal - analysis
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Beschreibung
Zusammenfassung:	EtOH extracts of the rhizomes and aboveground portion of Trillium grandiflorum showed significant antifungal activity. Bioassay directed fractionation has led to the identification of the active components as the saponin glycosides 1 and 3.
ISSN:	0163-3864 1520-6025
DOI:	10.1021/np50055a013