Meroterpenes from the Ascidian Aplidium a ff. d ensum

Meroterpenes from the Ascidian Aplidium a ff. d ensum

Chemical investigation of the ascidian Aplidium aff. densum collected at Masirah Island, Oman, has resulted in the isolation of five meroterpenes: two new ones, methoxyconidiol (1) and didehydroconicol (2), and three related, known compounds, 3−5. The structures of 1 and 2 were determined by a combi...

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Veröffentlicht in:Journal of natural products (Washington, D.C.) D.C.), 2005-09, Vol.68 (9), p.1412-1415
Hauptverfasser: Simon-Levert, Annabel, Arrault, Alban, Bontemps-Subielos, Nataly, Canal, Christophe, Banaigs, Bernard
Format: Artikel
Sprache:eng
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Zusammenfassung:Chemical investigation of the ascidian Aplidium aff. densum collected at Masirah Island, Oman, has resulted in the isolation of five meroterpenes: two new ones, methoxyconidiol (1) and didehydroconicol (2), and three related, known compounds, 3−5. The structures of 1 and 2 were determined by a combination of mass spectrometry and one- and two-dimensional high-field NMR techniques. Their biological activities against bacteria and human lymphoblastic cell lines were evaluated.
ISSN:0163-3864
1520-6025
DOI:10.1021/np050110p