New Dihydroalkylhexenones from Lannea e dulis

New Dihydroalkylhexenones from Lannea e dulis

Activity-guided isolation of radical-scavenging compounds from the dichloromethane extract of the root bark of Lannea edulis led to isolation of two known bioactive alkylphenols [cardonol 7 (1) and cardonol 13 (2)], and three new dihydroalkylhexenones were also isolated (3−5). Their structures were...

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Veröffentlicht in:Journal of natural products (Washington, D.C.) D.C.), 2003-04, Vol.66 (4), p.578-580
Hauptverfasser: Queiroz, Emerson F, Kuhl, Celestina, Terreaux, Christian, Mavi, Stephen, Hostettmann, Kurt
Format: Artikel
Sprache:eng
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Zusammenfassung:Activity-guided isolation of radical-scavenging compounds from the dichloromethane extract of the root bark of Lannea edulis led to isolation of two known bioactive alkylphenols [cardonol 7 (1) and cardonol 13 (2)], and three new dihydroalkylhexenones were also isolated (3−5). Their structures were elucidated by spectroscopic and chemical methods. The absolute configuration of 4 was determined by the Mosher ester method.
ISSN:0163-3864
1520-6025
DOI:10.1021/np0202428