Isolation and Characterization of Trioxyethylene-Encapsulated Gold Nanoclusters Functionalized with a Single DNA Strand
A scalable means of isolating significant quantities of trioxyethylene-encapsulated gold nanoclusters (GNCs) labeled with a single DNA strand is demonstrated. Quantitative characterization of the product is obtained using UV−vis absorbance spectroscopy. These methods of isolation and characterizatio...
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Veröffentlicht in: | Nano letters 2004-04, Vol.4 (4), p.737-740 |
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Hauptverfasser: | , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | A scalable means of isolating significant quantities of trioxyethylene-encapsulated gold nanoclusters (GNCs) labeled with a single DNA strand is demonstrated. Quantitative characterization of the product is obtained using UV−vis absorbance spectroscopy. These methods of isolation and characterization of singly functionalized GNC−ssDNA conjugates are expected to aid development of nanoscience applications that use DNA molecular recognition for guiding self-assembly. |
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ISSN: | 1530-6984 1530-6992 |
DOI: | 10.1021/nl0499591 |