An Artificial Nanopore for Molecular Sensing

We have used micromolding techniques to embed a nanoscale pore in PDMS. This novel design allows rapid and reproducible fabrication of pores, is extremely flexible, and can be modified both structurally and chemically for a variety of single-molecule detection applications. We demonstrate the capabi...

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Veröffentlicht in:	Nano letters 2003-01, Vol.3 (1), p.37-38
Hauptverfasser:	Saleh, Omar A, Sohn, Lydia L
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Diverse techniques Fundamental and applied biological sciences. Psychology Molecular and cellular biology
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	We have used micromolding techniques to embed a nanoscale pore in PDMS. This novel design allows rapid and reproducible fabrication of pores, is extremely flexible, and can be modified both structurally and chemically for a variety of single-molecule detection applications. We demonstrate the capabilities of the device to sense electronically single DNA molecules.
ISSN:	1530-6984 1530-6992
DOI:	10.1021/nl0255202